It seems a very common issue and I'm stunned reading that WON'T FIX!
Briefly, I noted that global shortcut keys (such as Ctrl+Space I use to call my favourite launcher) doesn't work when focus is on certain applications windows (gnome-terminal or gedit, for example) but only when I'm running Wayland.
Moreover, if I use xfce4-panel and the window buttons element, the button won't appear for the same apps.
With other apps (chromium, thunderbird, synapse, for example) both issues are not presenting.