< Radiation Oncology < Rectum


Rectal Cancer Review


  • Surgical margin
    • R0 typically defined as >1 mm
    • Prognostic impact on LR and OS
  • Neoadjuvant chemo-RT
    • Superior over adjuvant chemo-RT: German Rectal Trial
    • Superior over neoadjuvant RT alone: EORTC 22921 and FFCD 9203
      • No difference in OS, 5-year ~65%
      • Significant benefit for LR 16-17% -> 8-9%
      • R0 ~90%; ypCR 15-20%
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