I'd like to boot Ubuntu (or edubuntu) from a USB device, and store data on the device for future use, as well as install software, drivers, etc. According to this answer, a Full Install will get better performance and allow drivers to be installed, making it a better fit for my use case over a Persistent Install.
When I was previously looking to putting Linux on a usb key, a concern was read/write cycles and unnecessarily spending them updating swap or otherwise using temporary files. The hardware I'm considering using (most of the time) would have plenty of RAM, so I'm fine with limiting myself some there.
Is there a way to do the [Ed]Ubuntu install on a flash drive that limits/reduces/eliminates frequent writes to the flash storage device?
... or is this all completely overkill? I admit I'd like the option to use slightly older hardware, and slightly older USB keys. So yes, I'm sure I could get a new flash drive for a great price on sale. I'm not looking to spend the money though. If it helps, consider a use case where an educational organization doesn't have the discretionary funds to significantly update their hardware every few years, and so I'm volunteering my time to extend the life of their resources on hand.
If it matters, the initial consideration for install is 16.04 LTS, or 18.04 LTS.