Why Bother?
The right question is why do you want to convert the spaces (optionally UPPER case) in multi-word filenames into something else?
Normal Desktop Use
If you are a desktop user who uses LibreOffice to create and edit documents for personal, then I don't see any reason to change. You will probably only use the File > Open dialog in LibreOffice to open the files. Or you may use Nautilus (Gnome Files) to go to the folder and double click on the a file to open it. These normal day-to-day activities do not require removal of space (optionally UPPER case) from filenames.
If you occasionally (or regularly) share these files with Windows or Mac users, then too I don't see any problem. All modern OSs can handle spaces in filenames. I get MSWord files from Windows users everyday that have spaces (and UPPER cases) in names. I open them in LibreOffice without any need to rename them.
Command-line and Scripts
If you use command-line or scripts to manipulate these files everyday, then it may make sense to convert them using some convention as described in other answers. If you like to torture yourself you can always type
Change\ Of\ Address\ Cards.odt
on a terminal. Or enclose it in quotes:
"Change Of Address Cards.odt"
If you can write your own bash (or any other) scripts then you can probably make the script smart enough to use quotes to enclose file names with spaces.
In this case, having spaces and UPPER cases in file names may need a bit of extra typing or more careful script writing, but may not be a deal breaker.
If you work with scripts written by others, and these scripts don not handle space and UPPER cases in filenames well, then you need to change the filenames.
Web based document repository
If you are building a web based document storage, where the filenames will be stored in a database, and they will be accessed as web URL, then it may be a problem if you have spaces and UPPER cases in the names as URLs don't handle spaces and UPPER cases well. The web-server you use may or may not make the conversion for you. If it does not, you definitely need to rename your files and you need to create and adhere to a convention to be consistent.
Others
There may be other scenarios where you may want to get rid of spaces in filenames. In those cases, your specific needs may determine what conversion convention you will need to follow.
Hope this helps