Does not seem to affect the machine when I am using it. I suspect it is causing the boot time to be longer than necessary though. I am a new user and thus will need to be guided like a little child. I'm pretty sure the machine is waiting for me to do something but I am too ignorant to know what that is. Here is the complete notification on boot screen.
[ 0.004670] __common_interrupt: 1.55 No irq handler for vector
[ 0.004670] __common_interrupt: 2.55 No irq handler for vector
[ 0.004670] __common_interrupt: 3.55 No irq handler for vector
[ 0.698565] platform MSFT0101:00: failed to claim resource 0: [mem 0x9fb6e000
-0x9fc6dfff]
[ 0.698582] acpi MSFT0101:00: platform device creation failed: -16
[ 0.865631] tpm_crb MSFT0101:00: can't request region for resource [mem 0x9fb
6e000-0x9fc6dfff]