This is my "linux emergency cheat sheet":
1. Non responsive application
SUPER --> type in System Monitor --> RETURN --> find process --> right click --> Kill Process
or
ALT + F2 --> type in xkill
--> x marks the spot (or in this case frozen app)
or
CTRL + ALT + T --> type in top
--> find process ID --> k PID
where PID = process ID
Effect: This kills the program.
2. Non responsive desktop
CTRL + ALT + F1 --> type in sudo service lightdm restart
Effect: This kills the session and starts a new one.
3. Non responsive system
LAST RESORT. ONLY USE WHEN EVERYTHING ELSE FAILS:
Hold ALT + SysRq down and hit the following keys in the given order:
R --> E --> I --> S --> U -->B
This is where you find the magic SysRq key:

Effect: This restarts the system but only after performing the following actions:
unRaw (take control of keyboard back from X),
tErminate (send SIGTERM to all processes, allowing them to terminate gracefully),
kIll (send SIGKILL to all processes, forcing them to terminate immediately),
Sync (flush data to disk),
Unmount (remount all filesystems read-only),
reBoot.
Bonus mnemonic: Reboot Even If System Utterly Broken