It depends. Like @Gui said, basically no.
However, if you install WINE (Wine Is Not an Emulator), it allows you to run Windows programs and the necessary drivers, system files, and whatnot that you might need to run the program. I had a Windows game I attempted to run under WINE, and it was very laggy and the Framerate was awful.
Check out the link @Gui gave you, and try from there.
PS...How to install WINE (and you will also want Winetricks):
Enter this at the terminal:
sudo apt-get update
sudo apt-get upgrade
sudo apt-get install wine winetricks
That will make sure everything is up to date before and after installing WINE/Winetricks.