I installed the latest Ubuntu in the latest Virtualbox. It is slow: frames are visible in animations and the mouse flickers.
This question is different from many others on the net that suggest enabling 3D support. "/usr/lib/nux/unity_support_test -p" returns that Unity 3D IS supported. Everything seems as it is supposed to be.
In Virtualbox 3D acceleration is enabled, 2D acceleration is greyed out (absent). I gave it 64MB of video RAM.
This is on an i5 with HD Graphics 2500, on W8.1+update plus latest HD drivers. Nothing uncommon: this should be in the Ubuntu release notes.